RESEARCH INTERESTS

Our research group focuses on the development of functional biopolymers through the rational design, aiming to address the major scientific problems in the fields of drug delivery and cancer therapy, and promotes the clinical translation of biomedical polymers.

EDUCATION

2010–2016, Ph.D., Changchun Institute of Applied Chemistry, Chinese Academy of Sciences (Supervisor: Professor Xuesi Chen)

2006–2010, B.S., College of Chemistry and Chemical Engineering, Nanjing University

PROFESSIONAL EXPERIENCE

2021–present, Assistant Professor, School of Materials Science and Engineering, Peking University

2018–2021, Postdoc, Department of Bioengineering, University of Washington (Advisor: Prof. Suzie H Pun)

2017–2018, Postdoc, Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign (Advisor: Prof. Jianjun Cheng)

2016–2017, Postdoc, FUNSOM, Soochow University (Advisor: Prof. Jianjun Cheng)

SELECTED PUBLICATIONS

(1) Lv Shixian; Sylvestre Meilyn; Song Kefan; Pun H. Suzie; Development of D-melittin polymeric nanoparticles for anti-cancer treatment, Biomaterials, 2021, 277: 121076

(2) Lv Shixian; Sylvestre Meilyn; Prossnitz N. Alexander; Yang F. Lucy; Pun H. Suzie ; Design of Polymeric Carriers for Intracellular Peptide Delivery in Oncology Applications, Chem. Rev., 2021, 121(18): 11653-11698

(3) Lv Shixian; Wu Yuchen; Cai Kaimin; He Hua; Li Yongjuan; Lan Min; Chen Xuesi; Cheng Jianjun; Yin Lichen ; High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor-Receptor Coordination Interactions, J. Am. Chem. Soc., 2018, 140(4): 1235-1238

(4) Lv, Shixian; Tang, Zhaohui; Song, Wantong; Zhang, Dawei; Li, Mingqiang; Liu, Huaiyu; Cheng, Jianjun; Zhong, Wu; Chen, Xuesi ; Inhibiting Solid Tumor Growth In Vivo by Non-Tumor-Penetrating Nanomedicine, SMALL, 2017, 13(12): 1600954

(5) Lv Shixian; Kim Hojun; Song Ziyuan; Feng Lin; Yang Yingfeng; Baumgartner Ryan; Tseng Kuan-Ying; Dillon J. Shen; Leal Cecilia; Yin Lichen; Cheng Jianjun ; Unimolecular Polypeptide Micelles via Ultrafast Polymerization of N-Carboxyanhydrides, J. Am. Chem. Soc., 2020, 142(19): 8570-8574